Research has shown that the activation of brown fat is related to preventing obesity.
A study examining the changes in mice when suppressing a specific protein related to brown fat deactivation has been published in the Nature Metabolism journal.
According to the research, the global obese population exceeds 1 billion. Obesity harms overall health and increases the risk of various diseases, so it must be actively managed.
Recently, brown fat has gained attention for its role in supporting our body’s metabolic health. Mammals, including humans, have two types of fat tissues—white and brown. White fat stores calories and an increase in white fat can lead to obesity and other health problems. On the other hand, brown fat converts calories into heat and consumes them.
The research indicates that activating brown fat helps reduce the risk of cardiovascular and metabolic diseases.
The researchers investigated whether activating brown fat helps reduce the risk of obesity through experiments on mice. They focused on a protein called AC3-AT related to brown fat deactivation. AC3-AT protein is produced in brown fat when it is activated and stops the activity of brown fat.
The researchers deactivated the AC3-AT protein in the mouse model, allowing the activity of brown fat to continue. As a result, calorie consumption increased in mice, metabolism sped up, and an effect of obesity prevention was observed.
Based on these results, the researchers concluded that there is an effect of preventing obesity when brown fat is activated.
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